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Tabloid research for the masses (27/01/22 09:54:32)
    Leaching of toxins from food containers will always be a concern. History has some frightening examples, such as lead from soldered seams leaching into canned foods and causing toxicity

    https://www.bmj.com/content/339/bmj.b5038

    or cadmium eluted by fruit juices from the glacing of fancy handmade ceramic jugs or cups

    https://ifst.onlinelibrary.wiley.com/doi/abs/10.1111/jfpp.15750
    https://www.winchesterhospital.org/health-library/article?id=120796

    (Precautions: - focus on lead:
    https://ehs.princeton.edu/health-safety-the-campus-community/art-theater-safety/art-safety/ceramics)

    So leaching poisonous elements from food containers is a real hazard, now generally avoidable. The elimination mechanisms may be insufficient to clear completely a daily intake. So even low-grade exposure is a problem.I suppose nutrition is a point here: Plentiful availability of the amino acid cysteine - or methionine - will contribute to binding the metals in a safe place and may serve as a starting point for elimination through bile.

    OK - enough.

    These days focus is on plastics. To have an easily-published article one needs spectacular results. So you take food containers, or non-food containers and treat them harshly. Then you take what you get and put them into cell cultures of your target tissue.

    What you do not do, is
    1) measuring your substances in the actual foods in the containers. Most likely you will be able to find anything: (remember: those containers have been approved as food containers, so they are already considered safe enough.).
    2) measuring the substances in blood of test animals or humans given realistic amounts of the food in question.
    3) test the bioavailability of the substances you have found, to see how much - if anything - escapes the protection systems in the intestinal wall and the liver, and the distribution - to see how much reaches target tissues, and how much is sequestered innocuoously in non-sensitive organs such as muscle. And finally: Is there evidence of accumulation?

    In academic research, I venture, such things are never done. The methods are difficult, the levels are most likely below any detection limit, even with Orbitrap(R) instruments, and the results will be unpublishable because the findings will be zero.

    Any examples?
    https://pubs.acs.org/doi/10.1021/acs.est.1c01103#
    https://pubs.acs.org/doi/10.1021/acs.est.1c06316
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Tabloid research for the masses